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A middle-aged couple suspects foul play when their neighbor's wife suddenly drops dead.

Quirky and rebellious April Burns lives with her boyfriend in a low-rent New York City apartment miles away from her emotionally distant family. But when she discovers that her mother has a fatal form of breast cancer, she invites the clan to her place for Thanksgiving. While her father struggles to drive her family into the city, April -- an inexperienced cook -- runs into kitchen trouble and must ask a neighbor for help.

Between two Thanksgivings, Hannah's husband falls in love with her sister Lee, while her hypochondriac ex-husband rekindles his relationship with her sister Holly.

When a young couple buys their dream home, they have no idea what the sweet little old lady upstairs is going to put them through!

A divorced writer from the Midwest returns to her hometown to reconnect with an old flame, who's now married with a family.