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Fashion designer Joanna Crane leads a double life. By night she is China Blue, a prostitute who's attracted the attention of a sexually frustrated private detective, and a psychopathic priest in possession of a murderous sex toy.

Ocho is accidentally captured by a drug trafficking cartel who use Chinese women to smuggle drugs into Japan by hiding it in their vaginas. She is tortured, and manages to escape, fighting both the male yakuzas and a gang of female thieves.

The continuation of Joe's sexually dictated life delves into the darker aspects of her adult life and what led to her being in Seligman's care.

A submissive hooker goes about her trade, suffering abuse at the hands of Japanese salarymen and Yakuza types. She's unhappy about her work, and is apparently trying to find some sort of appeasement for the fact that her lover has married.

A man named Seligman finds a fainted wounded woman in an alley and he brings her home. She tells him that her name is Joe and that she is nymphomaniac. Joe tells her life and sexual experiences with hundreds of men since she was a young teenager while Seligman tells about his hobbies, such as fly fishing, reading about Fibonacci numbers or listening to organ music.