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Happy young married couple Paige and Leo are, well, happy. Then a car accident puts Paige into a life-threatening coma. Upon awakening she has lost the previous five years of memories, including those of her beloved Leo, her wedding, a confusing relationship with her parents, or the ending of her relationship with her ex-fiance. Despite these complications, Leo endeavors to win her heart again and rebuild their marriage.

After a car crash, criminal psychologist Dr. Miranda Grey regains consciousness only to find that she's a patient in the same mental institution that currently employs her. She's been accused of murdering her husband Dr. Douglas Grey — but she has no memory of committing the crime. As she tries to regain her memory and convince her co-worker, Dr. Pete Graham, of her innocence, a vengeful spirit uses her as an earthly pawn, which further convinces everyone of her guilt.

Rachel Watson, devastated by her recent divorce, spends her daily commute fantasizing about the seemingly perfect couple who live in a house that her train passes every day, until one morning she sees something shocking happen there and becomes entangled in the mystery that unfolds.

Wealthy Sunny von Bülow lies brain-dead, husband Claus guilty of attempted murder; but he says he's innocent and hires Alan Dershowitz for his appeal.

Soon after a veteran returns from war, his cheating wife is found dead. He evades police in an attempt to find the real murderer.