The tumultuous presidency of 19th-president Andrew Johnson is chronicled in this biopic. The story begins with Johnson's boyhood and covers his early life. During the Civil War, Johnson stays a staunch Unionist and upon Lincoln's reelection in 1864, becomes his Vice President. After Lincoln's assassination, Johnson becomes the President and became the first U.S. president ever to be impeached.

Two years into the outbreak, SICK roam the land and the remaining survivors struggle day-to-day trying to rebuild civilization. With the SICK more active at night time, three people need to seek shelter in an empty home.