A British woman visits her husband at the Mexican mine he is attempting to reopen and discovers that the workers refuse to enter the mine, fearing an ancient curse. The couple enter the mine to prove there is no danger and inadvertently release a demon which possesses people's left hands and forces them to behave in a suitably diabolical manner.

A Latino family new to Los Angeles find itself in trouble when the husband is arrested for a murder he didn't commit. His pregnant wife winds up in the hospital, and his little daughter is kidnapped by a child molester.

This is the story of a man who, for work reasons, must travel to a small town in Michoacán called Purocuero. There, after a string of affairs with several women—all sharing the same name, Ignacia—he ultimately marries the only virgin in town.