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Rizwan Khan, a Muslim from the Borivali section of Mumbai, has Asperger's syndrome. He marries a Hindu single mother, Mandira, in San Francisco. After 9/11, Rizwan is detained by authorities at LAX who treat him as a terrorist because of his condition and his race.

Dr. Raj Bothra faced 54 federal charges at age 79 before being cleared by a unanimous jury verdict in June 2022. The doctor spent more than 1,300 days incarcerated while repeatedly denied bail.