Asuka Goda is a 40-year-old pastry chef who runs a sweets store. She works with pastry chef Seiya Hanada, who is younger than her, and Kenichi Gonda, who wants to become a pastry chef. One day, Seiya Hanada confesses to Asuka Goda about his feelings for her. Her situation brings back bad memories to what happened 5 years earlier. At that time, Asuka Goda was in an affair with store owner Junji Awai and also in a relationship with gym trainer Shunsuke Nomura. Asuka Goda decides to go to mysterious "Clinic Love Doc." The clinic lets people know everything about love with a gene test.

Rino Sakuragi (Yuna Taira) is a high school student. She is good friends with Ren Kiritani (Alan Shirahama) who attends the same high school. They have been close since their middle school days. Rino holds special feelings for Ren Kiritani, but she is unable to tell him how she feels because he is popular. One day, Ren confesses to Rino that he likes her. They begin to date and enjoy their time together, but Rino is diagnosed with ALS (amyotrophic lateral sclerosis).