When two corrupt police officers investigate the brutal murder of a young girl, tensions come to a head in their small, racially-segregated town.

After a booking mistake, four drag queens find themselves performing for a mostly unwelcoming crowd, but when vampires attack, the crowd looks to the queens to save the day.

Based on the biblical story of Abraham and Isaac, from Genesis: “God promised Sarah and Abraham they would have a son, even though she was past childbearing age.” After Isaac is born, to test Abraham’s obedience, God instructs him to sacrifice his only son. As the pious Abraham begins to prepare for the ritual sacrifice, he is stopped by the angel of the Lord and Isaac’s life is spared at the last moment.