A touching true story which portrays a doctor who selflessly dedicated his personal fortune to spreading the smallpox vaccination for saving people's lives.

Yasuo (Hiroshi Abe) grew up as an orphan. He married a woman he loved and they had a son Akira (later played by Takumi Kitamura). Yasuo's life seemed great at the time, but his life totally changed after his wife died in accident. Since that time, Yasuo, who never experienced parents' love himself, has to raise his son Akira alone.

A detective in Toyama is forced to confront his painful past when he takes on a murder case involving his two estranged childhood friends.

In the turbulent last days of the Edo period, Kawai Tsugunosuke, a Japanese samurai serving the Makino clan of Nagaoka, dreamt of independence from the restraints of vassalship. Despite his progressive views and his desire for his estate to remain neutral during the Boshin Civil War, he was bound by loyalty and duty to the clan and was compelled to choose sides.

One day a young Brazilian man living in Japan crashes his car into the side of the house of a happy family. They take him in after realizing he had been beaten. As they get to know each other they find the bonds of family transcend blood and lineage.