Rome is ruled by two emperors, Julius Caesar and Nero, who perform all kinds of orgies to celebrate their vast war triumphs and are controlling alchemy to create a homunculus. This being commits a terrible crime for which the war hero Gaius Prolificus is blamed, who becomes a fugitive from Rome.

A new Christmas is coming for the Cabrera family, this time marked by assassinations, world-wide and a mysterious murderous orangutan.