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As a child, Popoy has always been an academic achiever. He dreams of becoming a nurse that would someday be able to help heal the sick and provide comfort to those who need it. He starts his journey with his grandmother who accepts sewing jobs to fill their daily needs, along with his educational requirements. The ups and downs of their life will determine Popoy's ways to achieve their dreams.

A small family living in the Sitio of Tamburong was in total misery.Jacob grew up witnessing and hearing every fight and arguments of his parents. Despite these circumstances, Jacob's Mother, Lani pretends to be fine in front of her son. With her strong love and devotion to the Patron Saint, San Vicente Ferrer of Vito , Lani was still able to smile.

There are two siblings living an ordinary life near at a Himoga-an bridge. Junjun the elder brother who carry out the needs of his little brother (Biboy) by means of painting and selling his artworks. Biboy, Junjun's younger brother who looks up to him, he seeks to learn how to paint to help his elder brother to meet their daily needs, until one day an incident happened that changed their lives.