In the future, the desert country of Turaqistan is torn by a riot after private corporation Tamerlane, owned by the former Vice President of the United States, has taken over. Brand Hauser, a hitman who suppresses his emotions by gobbling down hot sauce, is hired by the corporation's head to kill the CEO of their competitors.

Four pals are stuck in a rut in adulthood: Adam has just been dumped, Lou is a hopeless party animal, Nick is a henpecked husband, and Jacob does nothing but play video games in his basement. But they get a chance to brighten their future by changing their past after a night of heavy drinking in a ski-resort hot tub results in their waking up in 1986.

After his long-time girlfriend dumps him, a thirty-year-old record store owner seeks to understand why he is unlucky in love while recounting his "top five breakups of all time".

When the law fails to punish a fellow rancher that has abused his horses, a Wyoming horse trader sacrifices it all in a quest for justice.

A day in the life of a Chicago cab driver is examined as he picks up fares from the good and bad parts of the city and emotionally connects to many of his passengers.

Hitman Martin Blank becomes a moving target after he rebuffs a fellow assassin's invitation to form a union. On the advice of his quirky assistant and neurotic psychiatrist, Martin begrudgingly heads out to Grosse Pointe, Michigan for his ten-year high school reunion, where he soon comes across the woman he jilted on prom night.

A Hollywood actor grows tired of making the same corporate movies, so he moves to Argentina to find more experimental and meaningful work.