A twisted teenage prostitute and an equally deranged vicious killer manage to escape from the pen and embark on a non-stop orgy of violence and debauchery, all while hoping to make it across the border into Mexico in order to seek refuge with the mysterious Sister Gomez.

The story throws Elvis impersonators, Indians, modern cowboys, a 6-foot-tall blond assassin, a frat boy, a corrupt sheriff and a prostitute into a chase for a priceless American Indian artifact stolen during a poker game at an Indian casino