On board the train to Tokyo to meet her boyfriend Shoji, Nana Komatsu ("Hachi") happened to sit beside Nana Osaki who was traveling to Tokyo to fulfill her dreams of becoming a musician. The vocalist for her punk band "Blast", Nana aims for a major debut for "Blast" in Tokyo where her boyfriend, Ren, is the guitarist for a popular band "Trapnest". Sharing the same name "Nana", both girls quickly form a bond of friendship. Their paths cross again when they encounter each other while searching for accomodation in Tokyo. Eventually they decide to live together in the same unit and this further strengthens their bond as the two "Nana(s)" go through their love lives and career in Tokyo.
Two girls named Nana meet on a train to Tokyo. Nana K. aims to reunite with her boyfriend and Nana O. hopes to make it big in the music business. Despite their differences, the pair hit it off and become roommates.
Two girls with the same name but very different personalities share an apartment in this sequel to Nana. The rising fame of Nana Osaki's band, the Black Stones, is beginning to take a toll on the best friends' relationship. Meanwhile, Nana Komatsu struggles to make sense of her love triangle with Black Stones' guitarist Nobu and rival group Trapnest's bassist Takumi.
