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Giant anacondas inhabit remote jungles and rivers, where they attack intruders with lethal force. Expeditions in search of riches, cures, or secrets are repeatedly turned into battles for survival against the snakes.
A 'National Geographic' film crew is taken hostage by an insane hunter, who takes them along on his quest to capture the world's largest — and deadliest — snake.
A scientific expedition sets out for Borneo to seek a flower called the Blood Orchid, which could grant extended life. Meanwhile, they run afoul of snakes and each other.
A mercenary-for-hire accepts a mission from a billionaire to capture a dangerous snake that could possibly help cure a terminal illness.
A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.